Freeze dryers are widely used in the fields of medicine, biological products, food, blood products, and active substances. Of course, their application scale and fields are still expanding. Imported fully enclosed refrigeration unit is adopted, with strong water capture capacity.
The air-cooled heat dissipation method is adopted, and no water circulation cooling is required. The cold trap is an all-stainless steel structure, which can be used for sample pre-freezing.
The whole machine complies with GMP standards; temperature and time program control, the entire sample sublimation process realizes automatic temperature control; independent temperature measurement and control of each layer of samples, triple temperature control protection to ensure sample safety;
heating elements are made of special materials, with small thermal inertia, Uniform temperature; manual capping device, easy to operate, safe and reliable, suitable for pilot or mass production.
The freeze dryer is composed of a refrigeration system, a vacuum system, a heating system, and an electrical instrument control system. The main components are a drying box, a condenser, a refrigeration unit, a vacuum pump, and a heating/cooling device.
Here is a freeze-drying method, referred to as freeze-drying for short, which is to first freeze water-containing substances into a solid state, and then sublime the water in it from a solid state to a gaseous state to remove water and preserve the substance.
It is the freeze-drying process, which plays a key role in the manufacture of certain biological products and medicines.
During the operation of the freeze dryer, impurities such as moisture, dirt and solid powder will be generated in the refrigerant and refrigeration oil.
When the impurities exceed a certain amount, the orifice will be blocked. In order to avoid this situation, it is very necessary to install a drier filter on the refrigerant supply pipe.
In addition, the drying treatment of the drier can reduce the trace moisture in the refrigerant and protect the normal operation of the refrigeration system. Refrigerant evaporators, condensers and refrigerated oil for processing are necessary.
In addition, pre-freezing must be carried out before operation. Pre-freezing requires a -40°C low-temperature refrigerator, and the items to be dried are placed in a low-temperature refrigerator or liquid nitrogen, which generally takes about four hours, and can be observed directly from the outside.
After the items are completely frozen, the freeze-drying experiment can be carried out, and the items are quickly moved into the tray to ensure the freeze-drying effect.
There are several important parameters of the freeze dryer that should be paid special attention to. The daily use must be checked from the following important parameters:
1. The number of partitions in the drying room, the temperature of the partitions, and whether there are sundries in the drying room should be checked in time.
2. Whether the capping function is good, and whether the manual and automatic functions are good.
3. Has the material of the condenser changed?
4. Whether the function of the compressor of the cooling system is normal.
5. Whether the parameter settings of the monitor are normal.
Application of freeze dryer machine
